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KMID : 0355620200460040220
Journal of Korean Association of Oral and Maxillofacial Surgeons
2020 Volume.46 No. 4 p.220 ~ p.227
Oral rehabilitation of Papillon?Lefevre syndrome patients by dental implants: a systematic review
Atarbashi-Moghadam Fazele

Atarbashi-Moghadam Saede
Kazemifard Setare
Sijanivandi Soran
Namdari Mahshid
Abstract
Objectives: Papillon?Lefevre syndrome (PLS) is a rare autosomal recessive disorder. These patients lose their teeth at a young age and are in need of prosthetic rehabilitation. The aim of this systematic review was to assess the success of dental implant placement in these patients.

Materials and Methods: An electronic search was performed in PubMed Central, Scopus, and Web of Science using the keyword ¡°Papillon?Lefevre syndrome¡± AND ¡°dental implant¡± OR ¡°prosthodontics¡±. Articles reporting implant placement in patients with PLS until July 2019 were included.

Results: Assessment of the included 11 articles reporting 15 cases showed 136 implant placements in these patients. Implant failure occurred in 3 patients (20 implants). The peri-implantitis and failure rate was higher in the maxilla. Meta-analysis showed the probability of failure to be 7% (95% confidence interval [CI] 0%-31%) for maxillary implants and 2% (95% CI 0%-9%) for mandibular implants. The follow-up time ranged between 1 and 20 years. Healing after bone graft and implant placement in these patients was uneventful.

Conclusion: Dental implants may be a viable treatment option for PLS patients. Implantation can help preserve alveolar bone if the patients¡¯ immuno-logical and growing conditions are well-considered and proper oral hygiene and compliance with the maintenance program are continued.
KEYWORD
Papillon?Lefevre syndrome, Dental implants, Oral rehabilitation, Prosthodontics, Rapid progressive periodontitis
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